Changes in dermal fibroblasts from Abcc6−/− mice are present before and after the onset of ectopic tissue mineralization

Pseudoxanthoma elasticum (PXE), a rare genetic disease caused by mutations in the ABCC6 gene, is characterized by progressive calcification of elastic fibers in the skin, eyes and the cardiovascular system. The pathomechanisms of the mineralization is still obscure. Several hypotheses have been prop...

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Detalles Bibliográficos
Autores principales: Boraldi, Federica, Bartolomeo, Angelica, Li, Qiaoli, Uitto, Jouni, Quaglino, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057957/
https://www.ncbi.nlm.nih.gov/pubmed/24670382
http://dx.doi.org/10.1038/jid.2014.88

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057957/
https://www.ncbi.nlm.nih.gov/pubmed/24670382
http://dx.doi.org/10.1038/jid.2014.88

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