Stat3 binds to mitochondrial DNA and regulates mitochondrial gene expression in keratinocytes

The nuclear transcription factor Stat3 has recently been reported to have a localized mitochondrial regulatory function. Current data suggest that mitochondrial Stat3 (mitoStat3) is necessary for maximal mitochondrial activity and for Ras-mediated transformation independent of Stat3 nuclear activity...

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Detalles Bibliográficos
Autores principales: Macias, Everardo, Rao, Dharanija, Carbajal, Steve, Kiguchi, Kaoru, DiGiovanni, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057971/
https://www.ncbi.nlm.nih.gov/pubmed/24496235
http://dx.doi.org/10.1038/jid.2014.68

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057971/
https://www.ncbi.nlm.nih.gov/pubmed/24496235
http://dx.doi.org/10.1038/jid.2014.68

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