Cargando…

Stat3 binds to mitochondrial DNA and regulates mitochondrial gene expression in keratinocytes

The nuclear transcription factor Stat3 has recently been reported to have a localized mitochondrial regulatory function. Current data suggest that mitochondrial Stat3 (mitoStat3) is necessary for maximal mitochondrial activity and for Ras-mediated transformation independent of Stat3 nuclear activity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Macias, Everardo, Rao, Dharanija, Carbajal, Steve, Kiguchi, Kaoru, DiGiovanni, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057971/ https://www.ncbi.nlm.nih.gov/pubmed/24496235 http://dx.doi.org/10.1038/jid.2014.68

Ejemplares similares

Role of Stat3 in Skin Carcinogenesis: Insights Gained from Relevant Mouse Models
por: Macias, Everardo, et al.
Publicado: (2013)

Mitochondrial metabolism as a regulator of keratinocyte differentiation
por: Hamanaka, Robert B, et al.
Publicado: (2013)

Protein Tyrosine Phosphatases, TC-PTP, SHP1, and SHP2, Cooperate in Rapid Dephosphorylation of Stat3 in Keratinocytes Following UVB Irradiation
por: Kim, Dae Joon, et al.
Publicado: (2010)

Lin(neg) Sca-1(high) CD49f(high) prostate cancer cells derived from the Hi-Myc mouse model are tumor-initiating cells with basal-epithelial characteristics and differentiation potential in vitro and in vivo
por: Saha, Achinto, et al.
Publicado: (2016)

Cyclin‐dependent kinase 4 expression alters the number of keratinocyte stem cells in the mouse hair follicle
por: Kim, Sun Hye, et al.
Publicado: (2022)

Keratinocyte differentiation induces APOBEC3A, 3B, and mitochondrial DNA hypermutation
por: Wakae, Kousho, et al.
Publicado: (2018)

Mitochondrial fusion is required for regulation of mitochondrial DNA replication
por: Silva Ramos, Eduardo, et al.
Publicado: (2019)

Mitochondrial DNA variations and mitochondrial dysfunction in Fanconi anemia
por: Solanki, Avani, et al.
Publicado: (2020)

Perspective: mitochondrial STAT3 in cardioprotection
por: Kleinbongard, Petra
Publicado: (2023)

Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function
por: Szczesny, Bartosz, et al.
Publicado: (2014)

A role for keratins in supporting mitochondrial organization and function in skin keratinocytes
por: Steen, Kaylee, et al.
Publicado: (2020)

Effects of selenium on myocardial apoptosis by modifying the activity of mitochondrial STAT3 and regulating potassium channel expression
por: Zhang, Changjiang, et al.
Publicado: (2017)

Mitochondrial Stat3, the Need for Design Thinking
por: Yang, Rui, et al.
Publicado: (2016)

Selective Reduction in α‐Hydroxypalmitic Acid‐containing Sphingomyelin and Concurrent Increase in Hydroxylated Ceramides in Murine Skin Tumors Induced by an Initiation‐promotion Regimen
por: Kitano, Yukie, et al.
Publicado: (1996)

CLUH regulates mitochondrial biogenesis by binding mRNAs of nuclear-encoded mitochondrial proteins
por: Gao, Jie, et al.
Publicado: (2014)

STAT3 Undergoes Acetylation-dependent Mitochondrial Translocation to Regulate Pyruvate Metabolism
por: Xu, Yan S., et al.
Publicado: (2016)

A New Perspective: Mitochondrial Stat3 as a Regulator for Lymphocyte Function
por: Rincon, Mercedes, et al.
Publicado: (2018)

DNA synthesis determines the binding mode of the human mitochondrial single-stranded DNA-binding protein
por: Morin, José A., et al.
Publicado: (2017)

Yeast mitochondrial HMG proteins: DNA-binding properties of the most evolutionarily divergent component of mitochondrial nucleoids
por: Bakkaiova, Jana, et al.
Publicado: (2016)

Mitochondrial DNA depletion, mitochondrial mutations and high TFAM expression in hepatocellular carcinoma
por: Qiao, Lihua, et al.
Publicado: (2017)

Mgm101p Is a Novel Component of the Mitochondrial Nucleoid That Binds DNA and Is Required for the Repair of Oxidatively Damaged Mitochondrial DNA
por: Meeusen, Shelly, et al.
Publicado: (1999)

Cyclophilin 40 alters UVA-induced apoptosis and mitochondrial ROS generation in keratinocytes
por: Jandova, Jana, et al.
Publicado: (2013)

Quantification and Characterization of UVB-Induced Mitochondrial Fragmentation in Normal Primary Human Keratinocytes
por: Jugé, Romain, et al.
Publicado: (2016)

Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes
por: Chandramouleeswaran, Prasanna M., et al.
Publicado: (2020)

STAT6 in mitochondrial outer membrane impairs mitochondrial fusion by inhibiting MFN2 dimerization
por: Kim, Hyunmi, et al.
Publicado: (2022)

Mitochondrial DNA in the regulation of innate immune responses
por: Fang, Chunju, et al.
Publicado: (2015)

Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy
por: Kopinski, Piotr K., et al.
Publicado: (2019)

The Sorting of Mitochondrial DNA and Mitochondrial Proteins in Zygotes: Preferential Transmission of Mitochondrial DNA to the Medial Bud
por: Okamoto, Koji, et al.
Publicado: (1998)

STAT3 Regulates Mouse Neural Progenitor Proliferation and Differentiation by Promoting Mitochondrial Metabolism
por: Su, Yixun, et al.
Publicado: (2020)

Ultraviolet B, melanin and mitochondrial DNA: Photo-damage in human epidermal keratinocytes and melanocytes modulated by alpha-melanocyte-stimulating hormone
por: Böhm, Markus, et al.
Publicado: (2016)

RAGE Regulating Vascular Remodeling in Diabetes by Regulating Mitochondrial Dynamics with JAK2/STAT3 Pathway
por: Sun, Shengjia, et al.
Publicado: (2022)

Mitochondrial DNA and Inflammation in Alzheimer’s Disease
por: Galizzi, Giacoma, et al.
Publicado: (2023)

Preventing Mitochondrial Fission Impairs Mitochondrial Function and Leads to Loss of Mitochondrial DNA
por: Parone, Philippe A., et al.
Publicado: (2008)

Epigenetic Regulation of Gene Expression in Keratinocytes
por: Botchkarev, Vladimir A., et al.
Publicado: (2012)

Human herpesvirus type 1 and type 2 disrupt mitochondrial dynamics in human keratinocytes
por: Chodkowski, Marcin, et al.
Publicado: (2018)

Ultraviolet Radiation-Induced Mitochondrial Disturbances Are Attenuated by Metabolites of Melatonin in Human Epidermal Keratinocytes
por: Holtkamp, Chantal E., et al.
Publicado: (2023)

Methylation of mitochondrial DNA displacement loop region regulates mitochondrial copy number in colorectal cancer
por: Tong, Huan, et al.
Publicado: (2017)

Mitochondrial replacement to prevent the transmission of mitochondrial DNA disease
por: Herbert, Mary, et al.
Publicado: (2015)

Prevalence of rare mitochondrial DNA mutations in mitochondrial disorders
por: Bannwarth, Sylvie, et al.
Publicado: (2013)

The Maintenance of Mitochondrial DNA Integrity and Dynamics by Mitochondrial Membranes
por: Chapman, James, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9nhodmachit7h4aj2hucgu5ail