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SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I

SERPINB3 (SB3) is a serine protease inhibitor overexpressed in several malignancies of epithelial origin, including primary liver cancer, where it inhibits apoptosis through poorly defined mechanisms. In the present study we analyze the effect of SB3 on hepatoma cell death elicited by a panel of che...

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Detalles Bibliográficos
Autores principales: Ciscato, Francesco, Sciacovelli, Marco, Villano, Gianmarco, Turato, Cristian, Bernardi, Paolo, Rasola, Andrea, Pontisso, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058015/
https://www.ncbi.nlm.nih.gov/pubmed/24810714