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STAT3 down regulates LC3 to inhibit autophagy and pancreatic cancer cell growth

The dismal 5-year survival (<5%) for pancreatic cancer (PanCA) underscores the need for developing effective therapeutic options. Recent studies from our laboratory have shown that Nexrutine(®) (Nx), a bark extract from Phellodendron amurense exhibits excellent anticancer activity in human pancre...

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Detalles Bibliográficos
Autores principales: Gong, Jingjing, Muñoz, Amanda R., Chan, Daniel, Ghosh, Rita, Kumar, Addanki P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058024/
https://www.ncbi.nlm.nih.gov/pubmed/24796733