Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis

We scrutinized the effect of insulin receptor (INSR) in addition to IGF1R in PCa using in vitro and in vivo models. In-vitro overexpression of IGF1R and INSRA, but not INSRB increased cell proliferation, colony formation, migration, invasion and resistance to apoptosis in prostate cancer cells (DU14...

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Detalles Bibliográficos
Autores principales: Heidegger, Isabel, Kern, Johann, Ofer, Philipp, Klocker, Helmut, Massoner, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058040/
https://www.ncbi.nlm.nih.gov/pubmed/24809298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058040/
https://www.ncbi.nlm.nih.gov/pubmed/24809298

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