Aggresome formation is regulated by RanBPM through an interaction with HDAC6

In conditions of proteasomal impairment, the build-up of damaged or misfolded proteins activates a cellular response leading to the recruitment of damaged proteins into perinuclear aggregates called aggresomes. Aggresome formation involves the retrograde transport of cargo proteins along the microtu...

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Detalles Bibliográficos
Autores principales: Salemi, Louisa M., Almawi, Ahmad W., Lefebvre, Karen J., Schild-Poulter, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058076/
https://www.ncbi.nlm.nih.gov/pubmed/24795145
http://dx.doi.org/10.1242/bio.20147021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058076/
https://www.ncbi.nlm.nih.gov/pubmed/24795145
http://dx.doi.org/10.1242/bio.20147021

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