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EphA receptors regulate prostate cancer cell dissemination through Vav2–RhoA mediated cell–cell repulsion

Metastatic prostate cancer cells display EphB receptor-mediated attraction when they contact stromal fibroblasts but EphA-driven repulsion when they contact one another. The impact of these ‘social’ interactions between cells during cancer cell invasion and the signalling mechanisms downstream of Ep...

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Detalles Bibliográficos
Autores principales: Batson, Jennifer, Maccarthy-Morrogh, Lucy, Archer, Amy, Tanton, Helen, Nobes, Catherine D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058079/
https://www.ncbi.nlm.nih.gov/pubmed/24795148
http://dx.doi.org/10.1242/bio.20146601