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The dynamics of MAPK inactivation at fertilization in mouse eggs

Egg activation at fertilization in mammals is initiated by prolonged Ca(2+) oscillations that trigger the completion of meiosis and formation of pronuclei. A fall in mitogen-activated protein kinase (MAPK) activity is essential for pronuclear formation, but the precise timing and mechanism of declin...

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Detalles Bibliográficos
Autores principales: Gonzalez-Garcia, Jose Raul, Bradley, Josephine, Nomikos, Michail, Paul, Laboni, Machaty, Zoltan, Lai, F. Anthony, Swann, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058113/
https://www.ncbi.nlm.nih.gov/pubmed/24741069
http://dx.doi.org/10.1242/jcs.145045