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Effect of Ca(2+) Efflux Pathway Distribution and Exogenous Ca(2+) Buffers on Intracellular Ca(2+) Dynamics in the Rat Ventricular Myocyte: A Simulation Study
We have used a previously published computer model of the rat cardiac ventricular myocyte to investigate the effect of changing the distribution of Ca(2+) efflux pathways (SERCA, Na(+)/Ca(2+) exchange, and sarcolemmal Ca(2+) ATPase) between the dyad and bulk cytoplasm and the effect of adding exogen...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058148/ https://www.ncbi.nlm.nih.gov/pubmed/24971358 http://dx.doi.org/10.1155/2014/920208 |