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Effect of Ca(2+) Efflux Pathway Distribution and Exogenous Ca(2+) Buffers on Intracellular Ca(2+) Dynamics in the Rat Ventricular Myocyte: A Simulation Study

We have used a previously published computer model of the rat cardiac ventricular myocyte to investigate the effect of changing the distribution of Ca(2+) efflux pathways (SERCA, Na(+)/Ca(2+) exchange, and sarcolemmal Ca(2+) ATPase) between the dyad and bulk cytoplasm and the effect of adding exogen...

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Detalles Bibliográficos
Autores principales:	Pásek, Michal, Šimurda, Jiří, Orchard, Clive H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058148/ https://www.ncbi.nlm.nih.gov/pubmed/24971358 http://dx.doi.org/10.1155/2014/920208

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