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Biochemical and Neurotransmitters Changes Associated with Tramadol in Streptozotocin-Induced Diabetes in Rats

The incidence of diabetes is increasing worldwide. Chronic neuropathic pain occurs in approximately 25% of diabetic patients. Tramadol, an atypical analgesic with a unique dual mechanism of action, is used in the management of painful diabetic neuropathy. It acts on monoamine transporters to inhibit...

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Detalles Bibliográficos
Autores principales: Ezzeldin, Essam, Souror, Wafaa A. H., El-Nahhas, Toqa, Soudi, Abdel Nasser M. M., Shahat, Abdelaaty A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058222/
https://www.ncbi.nlm.nih.gov/pubmed/24971322
http://dx.doi.org/10.1155/2014/238780