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Biochemical and Neurotransmitters Changes Associated with Tramadol in Streptozotocin-Induced Diabetes in Rats
The incidence of diabetes is increasing worldwide. Chronic neuropathic pain occurs in approximately 25% of diabetic patients. Tramadol, an atypical analgesic with a unique dual mechanism of action, is used in the management of painful diabetic neuropathy. It acts on monoamine transporters to inhibit...
Autores principales: | Ezzeldin, Essam, Souror, Wafaa A. H., El-Nahhas, Toqa, Soudi, Abdel Nasser M. M., Shahat, Abdelaaty A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058222/ https://www.ncbi.nlm.nih.gov/pubmed/24971322 http://dx.doi.org/10.1155/2014/238780 |
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