IFN-γ-Secreting-Mesenchymal Stem Cells Exert an Antitumor Effect In Vivo via the TRAIL Pathway

Mesenchymal stem cells (MSCs) can exhibit either prooncogenic or antitumor properties depending on the context. Based on our previous study, we hypothesized that MSCs engineered to deliver IFN-γ would kill cancer cells through persistent activation of the TRAIL pathway. Human bone-marrow (BM-) deriv...

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Detalles Bibliográficos
Autores principales: Yang, Xinyuan, Du, Jingchun, Xu, Xia, Xu, Chun, Song, Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058226/
https://www.ncbi.nlm.nih.gov/pubmed/24971369
http://dx.doi.org/10.1155/2014/318098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058226/
https://www.ncbi.nlm.nih.gov/pubmed/24971369
http://dx.doi.org/10.1155/2014/318098

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