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Inhibitory Effect of Cinobufagin on L-Type Ca(2+) Currents, Contractility, and Ca(2+) Homeostasis of Isolated Adult Rat Ventricular Myocytes

Cinobufagin (CBG), a major bioactive ingredient of the bufanolide steroid compounds of Chan Su, has been widely used to treat coronary heart disease. At present, the effect of CBG on the L-type Ca(2+) current (I (Ca-L)) of ventricular myocytes remains undefined. The aim of the present study was to c...

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Detalles Bibliográficos
Autores principales: Li, Pinya, Song, Qiongtao, Liu, Tao, Wu, Zhonglin, Chu, Xi, Zhang, Xuan, Zhang, Ying, Gao, Yonggang, Zhang, Jianping, Chu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058228/
https://www.ncbi.nlm.nih.gov/pubmed/24977199
http://dx.doi.org/10.1155/2014/496705