Cargando…

High Glucose Induces Sumoylation of Smad4 via SUMO2/3 in Mesangial Cells

Recent studies have shown that sumoylation is a posttranslational modification involved in regulation of the transforming growth factor-β (TGF-β) signaling pathway, which plays a critical role in renal fibrosis in diabetic nephropathy (DN). However, the role of sumoylation in the regulation of TGF-β...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Xueqin, Gao, Chenlin, Huang, Wei, Yang, Maojun, Chen, Guo, Jiang, Lan, Gou, Fang, Feng, Hong, Ai, Na, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058256/
https://www.ncbi.nlm.nih.gov/pubmed/24971350
http://dx.doi.org/10.1155/2014/782625