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Olmesartan Attenuates Tacrolimus-Induced Biochemical and Ultrastructural Changes in Rat Kidney Tissue

Tacrolimus, a calcineurin inhibitor, is clinically used as an immunosuppressive agent in organ transplantation, but its use is limited due to its marked nephrotoxicity. The present study investigated the effect of olmesartan (angiotensin receptor blocker) on tacrolimus-induced nephrotoxicity in rats...

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Detalles Bibliográficos
Autores principales: Al-Harbi, Naif O., Imam, Faisal, Al-Harbi, Mohammed M., Iqbal, Muzaffar, Nadeem, Ahmed, Sayed-Ahmed, Mohammed M., Alabidy, Ali D., Almukhallafi, Ali F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058524/
https://www.ncbi.nlm.nih.gov/pubmed/24987695
http://dx.doi.org/10.1155/2014/607246