Promoter Region Hypermethylation and mRNA Expression of MGMT and p16 Genes in Tissue and Blood Samples of Human Premalignant Oral Lesions and Oral Squamous Cell Carcinoma

Promoter methylation and relative gene expression of O(6)-methyguanine-DNA-methyltransferase (MGMT) and p16 genes were examined in tissue and blood samples of patients with premalignant oral lesions (PMOLs) and oral squamous cell carcinoma (OSCC). Methylation-specific PCR and reverse transcriptase P...

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Detalles Bibliográficos
Autores principales: Bhatia, Vikram, Goel, Madhu Mati, Makker, Annu, Tewari, Shikha, Yadu, Alka, Shilpi, Priyanka, Kumar, Sandeep, Agarwal, S. P., Goel, Sudhir K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058681/
https://www.ncbi.nlm.nih.gov/pubmed/24991542
http://dx.doi.org/10.1155/2014/248419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058681/
https://www.ncbi.nlm.nih.gov/pubmed/24991542
http://dx.doi.org/10.1155/2014/248419

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