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Hsp90 Picks PIKKs via R2TP and Tel2
Phosphatidylinositol-3 kinase-like kinases (PIKKs) are dependent on Hsp90 for their activation via the R2TP complex and Tel2. In this issue of Structure, Pal and colleagues present the molecular mechanism by which PIKKs are recruited to Hsp90.
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cell Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058748/ https://www.ncbi.nlm.nih.gov/pubmed/24918336 http://dx.doi.org/10.1016/j.str.2014.05.012 |