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Hsp90 Picks PIKKs via R2TP and Tel2

Phosphatidylinositol-3 kinase-like kinases (PIKKs) are dependent on Hsp90 for their activation via the R2TP complex and Tel2. In this issue of Structure, Pal and colleagues present the molecular mechanism by which PIKKs are recruited to Hsp90.

Detalles Bibliográficos
Autor principal: Vaughan, Cara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058748/
https://www.ncbi.nlm.nih.gov/pubmed/24918336
http://dx.doi.org/10.1016/j.str.2014.05.012