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Hsp90 Picks PIKKs via R2TP and Tel2
Phosphatidylinositol-3 kinase-like kinases (PIKKs) are dependent on Hsp90 for their activation via the R2TP complex and Tel2. In this issue of Structure, Pal and colleagues present the molecular mechanism by which PIKKs are recruited to Hsp90.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058748/ https://www.ncbi.nlm.nih.gov/pubmed/24918336 http://dx.doi.org/10.1016/j.str.2014.05.012 |
| _version_ | 1782321165078888448 |
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| author | Vaughan, Cara K. |
| author_facet | Vaughan, Cara K. |
| author_sort | Vaughan, Cara K. |
| collection | PubMed |
| description | Phosphatidylinositol-3 kinase-like kinases (PIKKs) are dependent on Hsp90 for their activation via the R2TP complex and Tel2. In this issue of Structure, Pal and colleagues present the molecular mechanism by which PIKKs are recruited to Hsp90. |
| format | Online Article Text |
| id | pubmed-4058748 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | Cell Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-40587482014-06-17 Hsp90 Picks PIKKs via R2TP and Tel2 Vaughan, Cara K. Structure Preview Phosphatidylinositol-3 kinase-like kinases (PIKKs) are dependent on Hsp90 for their activation via the R2TP complex and Tel2. In this issue of Structure, Pal and colleagues present the molecular mechanism by which PIKKs are recruited to Hsp90. Cell Press 2014-06-10 /pmc/articles/PMC4058748/ /pubmed/24918336 http://dx.doi.org/10.1016/j.str.2014.05.012 Text en © 2014 The Author http://creativecommons.org/licenses/by/3.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/). |
| spellingShingle | Preview Vaughan, Cara K. Hsp90 Picks PIKKs via R2TP and Tel2 |
| title | Hsp90 Picks PIKKs via R2TP and Tel2 |
| title_full | Hsp90 Picks PIKKs via R2TP and Tel2 |
| title_fullStr | Hsp90 Picks PIKKs via R2TP and Tel2 |
| title_full_unstemmed | Hsp90 Picks PIKKs via R2TP and Tel2 |
| title_short | Hsp90 Picks PIKKs via R2TP and Tel2 |
| title_sort | hsp90 picks pikks via r2tp and tel2 |
| topic | Preview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058748/ https://www.ncbi.nlm.nih.gov/pubmed/24918336 http://dx.doi.org/10.1016/j.str.2014.05.012 |
| work_keys_str_mv | AT vaughancarak hsp90pickspikksviar2tpandtel2 |