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Myeloid Knockout of HIF-1α Does Not Markedly Affect Hemorrhage/Resuscitation-Induced Inflammation and Hepatic Injury
Background. Hypoxia-inducible factor-1α (HIF-1α) and NF-κB play important roles in the inflammatory response after hemorrhagic shock and resuscitation (H/R). Here, the role of myeloid HIF-1α in liver hypoxia, injury, and inflammation after H/R with special regard to NF-κB activation was studied. Met...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058797/ https://www.ncbi.nlm.nih.gov/pubmed/24991092 http://dx.doi.org/10.1155/2014/930419 |