Myeloid Knockout of HIF-1α Does Not Markedly Affect Hemorrhage/Resuscitation-Induced Inflammation and Hepatic Injury

Background. Hypoxia-inducible factor-1α (HIF-1α) and NF-κB play important roles in the inflammatory response after hemorrhagic shock and resuscitation (H/R). Here, the role of myeloid HIF-1α in liver hypoxia, injury, and inflammation after H/R with special regard to NF-κB activation was studied. Met...

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Detalles Bibliográficos
Autores principales: Wetzel, G., Relja, B., Klarner, A., Henrich, D., Dehne, N., Brühne, B., Lehnert, M., Marzi, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058797/
https://www.ncbi.nlm.nih.gov/pubmed/24991092
http://dx.doi.org/10.1155/2014/930419

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