Cargando…

Efficient Reprogramming of Mouse Fibroblasts to Neuronal Cells including Dopaminergic Neurons

Somatic cells were directly converted to functional neurons through the use of a combination of transcription factors, including Ascl1, Brn2, and Myt1l. However, a major limitation is the lack of a reliable source of cell-replacement therapy for neurological diseases. Here, we show that a combinatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Oh, Seung-ick, Park, Hang-soo, Hwang, Insik, Park, Han-kyul, Choi, Kyung-Ah, Jeong, Hyesun, Kim, Suhng Wook, Hong, Sunghoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058809/
https://www.ncbi.nlm.nih.gov/pubmed/24991651
http://dx.doi.org/10.1155/2014/957548