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Optimization of gene set annotations via entropy minimization over variable clusters (EMVC)

Motivation: Gene set enrichment has become a critical tool for interpreting the results of high-throughput genomic experiments. Inconsistent annotation quality and lack of annotation specificity, however, limit the statistical power of enrichment methods and make it difficult to replicate enrichment...

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Detalles Bibliográficos
Autores principales: Frost, H. Robert, Moore, Jason H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058919/
https://www.ncbi.nlm.nih.gov/pubmed/24574114
http://dx.doi.org/10.1093/bioinformatics/btu110