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Tertiary structure-based prediction of conformational B-cell epitopes through B factors
Motivation: B-cell epitope is a small area on the surface of an antigen that binds to an antibody. Accurately locating epitopes is of critical importance for vaccine development. Compared with wet-lab methods, computational methods have strong potential for efficient and large-scale epitope predicti...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058920/ https://www.ncbi.nlm.nih.gov/pubmed/24931993 http://dx.doi.org/10.1093/bioinformatics/btu281 |