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Accurate viral population assembly from ultra-deep sequencing data

Motivation: Next-generation sequencing technologies sequence viruses with ultra-deep coverage, thus promising to revolutionize our understanding of the underlying diversity of viral populations. While the sequencing coverage is high enough that even rare viral variants are sequenced, the presence of...

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Detalles Bibliográficos
Autores principales: Mangul, Serghei, Wu, Nicholas C., Mancuso, Nicholas, Zelikovsky, Alex, Sun, Ren, Eskin, Eleazar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058922/
https://www.ncbi.nlm.nih.gov/pubmed/24932001
http://dx.doi.org/10.1093/bioinformatics/btu295