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A combinatorial approach for analyzing intra-tumor heterogeneity from high-throughput sequencing data
Motivation: High-throughput sequencing of tumor samples has shown that most tumors exhibit extensive intra-tumor heterogeneity, with multiple subpopulations of tumor cells containing different somatic mutations. Recent studies have quantified this intra-tumor heterogeneity by clustering mutations in...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058927/ https://www.ncbi.nlm.nih.gov/pubmed/24932008 http://dx.doi.org/10.1093/bioinformatics/btu284 |