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Metabolome-scale prediction of intermediate compounds in multistep metabolic pathways with a recursive supervised approach

Motivation: Metabolic pathway analysis is crucial not only in metabolic engineering but also in rational drug design. However, the biosynthetic/biodegradation pathways are known only for a small portion of metabolites, and a vast amount of pathways remain uncharacterized. Therefore, an important cha...

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Detalles Bibliográficos
Autores principales: Kotera, Masaaki, Tabei, Yasuo, Yamanishi, Yoshihiro, Muto, Ai, Moriya, Yuki, Tokimatsu, Toshiaki, Goto, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058936/
https://www.ncbi.nlm.nih.gov/pubmed/24931980
http://dx.doi.org/10.1093/bioinformatics/btu265