Cargando…

New directions for diffusion-based network prediction of protein function: incorporating pathways with confidence

Motivation: It has long been hypothesized that incorporating models of network noise as well as edge directions and known pathway information into the representation of protein–protein interaction (PPI) networks might improve their utility for functional inference. However, a simple way to do this h...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Mengfei, Pietras, Christopher M., Feng, Xian, Doroschak, Kathryn J., Schaffner, Thomas, Park, Jisoo, Zhang, Hao, Cowen, Lenore J., Hescott, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058952/
https://www.ncbi.nlm.nih.gov/pubmed/24931987
http://dx.doi.org/10.1093/bioinformatics/btu263