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New directions for diffusion-based network prediction of protein function: incorporating pathways with confidence
Motivation: It has long been hypothesized that incorporating models of network noise as well as edge directions and known pathway information into the representation of protein–protein interaction (PPI) networks might improve their utility for functional inference. However, a simple way to do this h...
Autores principales: | Cao, Mengfei, Pietras, Christopher M., Feng, Xian, Doroschak, Kathryn J., Schaffner, Thomas, Park, Jisoo, Zhang, Hao, Cowen, Lenore J., Hescott, Benjamin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058952/ https://www.ncbi.nlm.nih.gov/pubmed/24931987 http://dx.doi.org/10.1093/bioinformatics/btu263 |
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