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AlignGraph: algorithm for secondary de novo genome assembly guided by closely related references

Motivation: De novo assemblies of genomes remain one of the most challenging applications in next-generation sequencing. Usually, their results are incomplete and fragmented into hundreds of contigs. Repeats in genomes and sequencing errors are the main reasons for these complications. With the rapi...

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Detalles Bibliográficos
Autores principales: Bao, Ergude, Jiang, Tao, Girke, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058956/
https://www.ncbi.nlm.nih.gov/pubmed/24932000
http://dx.doi.org/10.1093/bioinformatics/btu291