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AlignGraph: algorithm for secondary de novo genome assembly guided by closely related references
Motivation: De novo assemblies of genomes remain one of the most challenging applications in next-generation sequencing. Usually, their results are incomplete and fragmented into hundreds of contigs. Repeats in genomes and sequencing errors are the main reasons for these complications. With the rapi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058956/ https://www.ncbi.nlm.nih.gov/pubmed/24932000 http://dx.doi.org/10.1093/bioinformatics/btu291 |