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Influence of antiTNF-alpha antibody treatment on fracture healing under chronic inflammation

BACKGROUND: The overexpression of tumor necrosis factor (TNF)-α leads to systemic as well as local loss of bone and cartilage and is also an important regulator during fracture healing. In this study, we investigate how TNF-α inhibition using a targeted monoclonal antibody affects fracture healing i...

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Detalles Bibliográficos
Autores principales: Timmen, Melanie, Hidding, Heriburg, Wieskötter, Britta, Baum, Wolfgang, Pap, Thomas, Raschke, Michael J, Schett, Georg, Zwerina, Jochen, Stange, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059090/
https://www.ncbi.nlm.nih.gov/pubmed/24885217
http://dx.doi.org/10.1186/1471-2474-15-184