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Sequence Profiling of the Saccharomyces cerevisiae Genome Permits Deconvolution of Unique and Multialigned Reads for Variant Detection

Advances in high-throughput sequencing (HTS) technologies have accelerated our knowledge of genomes in hundreds of organisms, but the presence of repetitions found in every genome raises challenges to unambiguously map short reads. In particular, short polymorphic reads that are multialigned hinder...

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Detalles Bibliográficos
Autores principales: Jubin, Claire, Serero, Alexandre, Loeillet, Sophie, Barillot, Emmanuel, Nicolas, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059241/
https://www.ncbi.nlm.nih.gov/pubmed/24558267
http://dx.doi.org/10.1534/g3.113.009464