Identification of an Atg8-Atg3 Protein–Protein Interaction Inhibitor from the Medicines for Malaria Venture Malaria Box Active in Blood and Liver Stage Plasmodium falciparum Parasites

[Image: see text] Atg8 is a ubiquitin-like autophagy protein in eukaryotes that is covalently attached (lipidated) to the elongating autophagosomal membrane. Autophagy is increasingly appreciated as a target in diverse diseases from cancer to eukaryotic parasitic infections. Some of the autophagy ma...

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Detalles Bibliográficos
Autores principales: Hain, Adelaide U.P., Bartee, David, Sanders, Natalie G., Miller, Alexia S., Sullivan, David J., Levitskaya, Jelena, Meyers, Caren Freel, Bosch, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059259/
https://www.ncbi.nlm.nih.gov/pubmed/24786226
http://dx.doi.org/10.1021/jm401675a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059259/
https://www.ncbi.nlm.nih.gov/pubmed/24786226
http://dx.doi.org/10.1021/jm401675a

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