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Integrating Genomic, Transcriptomic, and Interactome Data to Improve Peptide and Protein Identification in Shotgun Proteomics

[Image: see text] Mass spectrometry (MS)-based shotgun proteomics is an effective technology for global proteome profiling. The ultimate goal is to assign tandem MS spectra to peptides and subsequently infer proteins and their abundance. In addition to database searching and protein assembly algorit...

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Detalles Bibliográficos
Autores principales: Wang, Xiaojing, Zhang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059263/
https://www.ncbi.nlm.nih.gov/pubmed/24792918
http://dx.doi.org/10.1021/pr500194t