Metal-deficient aggregates and diminished copper found in cells expressing SOD1 mutations that cause ALS

Disruptions in metal ion homeostasis have been described in association with amyotrophic lateral sclerosis (ALS) for a number of years but the precise mechanism of involvement is poorly understood. Metal ions are especially important to familial ALS cases caused by mutations in the metalloenzyme cop...

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Detalles Bibliográficos
Autores principales: Bourassa, Megan W., Brown, Hilda H., Borchelt, David R., Vogt, Stefan, Miller, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059277/
https://www.ncbi.nlm.nih.gov/pubmed/24982630
http://dx.doi.org/10.3389/fnagi.2014.00110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059277/
https://www.ncbi.nlm.nih.gov/pubmed/24982630
http://dx.doi.org/10.3389/fnagi.2014.00110

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