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MIF Family Members Cooperatively Inhibit p53 Expression and Activity

The tumor suppressor p53 is induced by genotoxic stress in both normal and transformed cells and serves to transcriptionally coordinate cell cycle checkpoint control and programmed cell death responses. Macrophage migration inhibitory factor (MIF) is an autocrine and paracrine acting cytokine/growth...

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Detalles Bibliográficos
Autores principales: Brock, Stephanie E., Rendon, Beatriz E., Xin, Dan, Yaddanapudi, Kavitha, Mitchell, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059697/
https://www.ncbi.nlm.nih.gov/pubmed/24932684
http://dx.doi.org/10.1371/journal.pone.0099795