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Overexpression of piRNA Pathway Genes in Epithelial Ovarian Cancer

The importance of the Piwi-interacting RNA (piRNA) pathway for germ cell maintenance, genome integrity, DNA methylation and retrotransposon control raises possible roles of this pathway in cancer. Indeed aberrant expression of human PIWI orthologs and Maelstrom has been observed in various cancers....

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Detalles Bibliográficos
Autores principales: Lim, Shu Ly, Ricciardelli, Carmela, Oehler, Martin K., De Arao Tan, Izza M. D., Russell, Darryl, Grützner, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059699/
https://www.ncbi.nlm.nih.gov/pubmed/24932571
http://dx.doi.org/10.1371/journal.pone.0099687