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Chondroitin Sulfate Proteoglycan CSPG4 as a Novel Hypoxia-Sensitive Marker in Pancreatic Tumors

CSPG4 marks pericytes, undifferentiated precursors and tumor cells. We assessed whether the shed ectodomain of CSPG4 (sCSPG4) might circulate and reflect potential changes in CSPG4 tissue expression (pCSPG4) due to desmoplastic and malignant aberrations occurring in pancreatic tumors. Serum sCSPG4 w...

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Detalles Bibliográficos
Autores principales: Keleg, Shereen, Titov, Alexandr, Heller, Anette, Giese, Thomas, Tjaden, Christine, Ahmad, Sufian S., Gaida, Matthias M., Bauer, Andrea S., Werner, Jens, Giese, Nathalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059742/
https://www.ncbi.nlm.nih.gov/pubmed/24932730
http://dx.doi.org/10.1371/journal.pone.0100178