A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome

Efficient duplication of the genome requires the concerted action of helicase and DNA polymerases at replication forks(1), to avoid stalling of the replication machinery and consequent genomic instability(2-4). In eukaryotes, the physical coupling between helicase and DNA polymerases remains poorly...

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Detalles Bibliográficos
Autores principales: Simon, Aline C., Zhou, Jin C., Perera, Rajika L., van Deursen, Frederick, Evrin, Cecile, Ivanova, Marina E., Kilkenny, Mairi L., Renault, Ludovic, Kjaer, Svend, Matak-Vinković, Dijana, Labib, Karim, Costa, Alessandro, Pellegrini, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059944/
https://www.ncbi.nlm.nih.gov/pubmed/24805245
http://dx.doi.org/10.1038/nature13234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059944/
https://www.ncbi.nlm.nih.gov/pubmed/24805245
http://dx.doi.org/10.1038/nature13234

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