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Modulation of NCC activity by low and high K(+) intake: insights into the signaling pathways involved
Modulation of Na(+)-Cl(−) cotransporter (NCC) activity is essential to adjust K(+) excretion in the face of changes in dietary K(+) intake. We used previously characterized genetic mouse models to assess the role of Ste20-related proline-alanine-rich kinase (SPAK) and with-no-lysine kinase (WNK)4 in...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059971/ https://www.ncbi.nlm.nih.gov/pubmed/24761002 http://dx.doi.org/10.1152/ajprenal.00255.2013 |