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Tumor suppressive miRNA-34a suppresses cell proliferation and tumor growth of glioma stem cells by targeting Akt and Wnt signaling pathways

MiRNA-34a is considered as a potential prognostic marker for glioma, as studies suggest that its expression negatively correlates with patient survival in grade III and IV glial tumors. Here, we show that expression of miR-34a was decreased in a graded manner in glioma and glioma stem cell-lines as...

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Detalles Bibliográficos
Autores principales: Rathod, Sachin S., Rani, Sandhya B., Khan, Mohsina, Muzumdar, Dattatraya, Shiras, Anjali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060015/
https://www.ncbi.nlm.nih.gov/pubmed/24944883
http://dx.doi.org/10.1016/j.fob.2014.05.002