Regulation of K(Ca)2.3 and endothelium-dependent hyperpolarization (EDH) in the rat middle cerebral artery: the role of lipoxygenase metabolites and isoprostanes

Background and Purpose. In rat middle cerebral arteries, endothelium-dependent hyperpolarization (EDH) is mediated by activation of calcium-activated potassium (K(Ca)) channels specifically K(Ca)2.3 and K(Ca)3.1. Lipoxygenase (LOX) products function as endothelium-derived hyperpolarizing factors (ED...

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Detalles Bibliográficos
Autores principales: Gauthier, Kathryn M., Campbell, William B., McNeish, Alister J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2014
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060036/
https://www.ncbi.nlm.nih.gov/pubmed/24949235
http://dx.doi.org/10.7717/peerj.414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060036/
https://www.ncbi.nlm.nih.gov/pubmed/24949235
http://dx.doi.org/10.7717/peerj.414

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