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Regulation of K(Ca)2.3 and endothelium-dependent hyperpolarization (EDH) in the rat middle cerebral artery: the role of lipoxygenase metabolites and isoprostanes
Background and Purpose. In rat middle cerebral arteries, endothelium-dependent hyperpolarization (EDH) is mediated by activation of calcium-activated potassium (K(Ca)) channels specifically K(Ca)2.3 and K(Ca)3.1. Lipoxygenase (LOX) products function as endothelium-derived hyperpolarizing factors (ED...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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PeerJ Inc.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060036/ https://www.ncbi.nlm.nih.gov/pubmed/24949235 http://dx.doi.org/10.7717/peerj.414 |