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Cordycepin-Enriched WIB801C from Cordyceps militaris Inhibits Collagen-Induced [Ca(2+)](i) Mobilization via cAMP-Dependent Phosphorylation of Inositol 1, 4, 5-Trisphosphate Receptor in Human Platelets

In this study, we prepared cordycepin-enriched (CE)-WIB801C, a n-butanol extract of Cordyceps militaris-hypha, and investigated the effect of CE-WIB801C on collagen-induced human platelet aggregation. CE-WIB801C dose-dependently inhibited collagen-induced platelet aggregation, and its IC(50) value w...

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Detalles Bibliográficos
Autores principales: Lee, Dong-Ha, Kim, Hyun-Hong, Cho, Hyun-Jeong, Yu, Young-Bin, Kang, Hyo-Chan, Kim, Jong-Lae, Lee, Jong-Jin, Park, Hwa-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060073/
https://www.ncbi.nlm.nih.gov/pubmed/25009703
http://dx.doi.org/10.4062/biomolther.2014.025