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Cordycepin-Enriched WIB801C from Cordyceps militaris Inhibits Collagen-Induced [Ca(2+)](i) Mobilization via cAMP-Dependent Phosphorylation of Inositol 1, 4, 5-Trisphosphate Receptor in Human Platelets
In this study, we prepared cordycepin-enriched (CE)-WIB801C, a n-butanol extract of Cordyceps militaris-hypha, and investigated the effect of CE-WIB801C on collagen-induced human platelet aggregation. CE-WIB801C dose-dependently inhibited collagen-induced platelet aggregation, and its IC(50) value w...
Autores principales: | Lee, Dong-Ha, Kim, Hyun-Hong, Cho, Hyun-Jeong, Yu, Young-Bin, Kang, Hyo-Chan, Kim, Jong-Lae, Lee, Jong-Jin, Park, Hwa-Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060073/ https://www.ncbi.nlm.nih.gov/pubmed/25009703 http://dx.doi.org/10.4062/biomolther.2014.025 |
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