β-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt Pathway

β-lapachone is a naturally occurring quinone that selectively induces apoptotic cell death in a variety of human cancer cells in vitro and in vivo; however, its mechanism of action needs to be further elaborated. In this study, we investigated the effects of β-lapachone on the induction of apoptosis...

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Detalles Bibliográficos
Autores principales: Yu, Hai Yang, Kim, Sung Ok, Jin, Cheng-Yun, Kim, Gi-Young, Kim, Wun-Jae, Yoo, Young Hyun, Choi, Yung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060078/
https://www.ncbi.nlm.nih.gov/pubmed/25009698
http://dx.doi.org/10.4062/biomolther.2014.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060078/
https://www.ncbi.nlm.nih.gov/pubmed/25009698
http://dx.doi.org/10.4062/biomolther.2014.026

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