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β-lapachone-Induced Apoptosis of Human Gastric Carcinoma AGS Cells Is Caspase-Dependent and Regulated by the PI3K/Akt Pathway

β-lapachone is a naturally occurring quinone that selectively induces apoptotic cell death in a variety of human cancer cells in vitro and in vivo; however, its mechanism of action needs to be further elaborated. In this study, we investigated the effects of β-lapachone on the induction of apoptosis...

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Detalles Bibliográficos
Autores principales:	Yu, Hai Yang, Kim, Sung Ok, Jin, Cheng-Yun, Kim, Gi-Young, Kim, Wun-Jae, Yoo, Young Hyun, Choi, Yung Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060078/ https://www.ncbi.nlm.nih.gov/pubmed/25009698 http://dx.doi.org/10.4062/biomolther.2014.026

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