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Luteolin Inhibits the Activity, Secretion and Gene Expression of MMP-3 in Cultured Articular Chondrocytes and Production of MMP-3 in the Rat Knee

We investigated whether luteolin affects the gene expression, secretion and activity of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as production of MMP-3 in the rat knee to evaluate the potential chondro-protective effects of luteolin. Rabbit articu...

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Detalles Bibliográficos
Autores principales: Kang, Bun-Jung, Ryu, Jiho, Lee, Choong Jae, Hwang, Sun-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060084/
https://www.ncbi.nlm.nih.gov/pubmed/25009705
http://dx.doi.org/10.4062/biomolther.2014.020