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Altered GABAergic markers, increased binocularity and reduced plasticity in the visual cortex of Engrailed-2 knockout mice

The maturation of the GABAergic system is a crucial determinant of cortical development during early postnatal life, when sensory circuits undergo a process of activity-dependent refinement. An altered excitatory/inhibitory balance has been proposed as a possible pathogenic mechanism of autism spect...

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Detalles Bibliográficos
Autores principales: Allegra, Manuela, Genovesi, Sacha, Maggia, Marika, Cenni, Maria C., Zunino, Giulia, Sgadò, Paola, Caleo, Matteo, Bozzi, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060086/
https://www.ncbi.nlm.nih.gov/pubmed/24987331
http://dx.doi.org/10.3389/fncel.2014.00163